Fulvestrant (ICI 182,780): High-Affinity Estrogen Recepto...
2026-01-20
Fulvestrant (ICI 182,780) is a potent, selective estrogen receptor antagonist used in ER-positive breast cancer research. It induces receptor degradation, enhances chemotherapy sensitivity, and supports studies on endocrine therapy resistance. This article details its mechanism, evidence base, and workflow applications.